232 - Clinical Application of Shear Wave Elastography to Diagnose and Evalua...

General Session: Diagnostic Imaging

Presented by: W. Tian

Author(s):

W. Tian(1), Q. Song(1), T. Chen(2), X. Han(1), J. Wang(1)

(1) Fourth Clinical Medical College of Peking University,Beijing Jishuitan Hospital, Department of Spine, Beijing, China
(2) Fourth Clinical Medical College of Peking University,Beijing Jishuitan Hospital, Department of Ultrasound, Beijing, China

Abstract

Background data: Shear wave elastography (SWE) is a novel, noninvasive, quantitative technique to estimate tissue elastic modulus in real time and expressed as Kpa. However, there is no study evaluating spinal cord elastic modulus.

Purpose: To evaluate the feasibility and diagnostic value of SWE in assessing Spinal Cord Dysfunction in patients with cervical spondylotic myelopathy, and analyze the factors that could influence the spinal cord elastic modulus. Patients and

Methods: 26 patients undergoing cervical laminoplasty for cervical spondylotic myelopathy were evaluated spinal cord elastic modulus using SWE. The elastic modulus of normal segment and the compressed segment spinal cord were measured twice in each patient. Functional outcomes were measured using JOA scores before the operation. Independent t-test was used to analyze the difference of normal segment elastic modulus in sex. Paired t-test was used to analyze the difference of the elastic modulus between the normal and compressed segment spinal cord. Pearson correlation was used to analyze the relationship between age, BMI and normal segment elastic modulus. Pearson correlation was also used to analyze the relationship between the JOA scores and the reduce ratio of elastic modulus. Using the intra-group correlation coefficient (ICC) to determine their intra-observer reproducibility.

Results: There was no significant difference in spinal cord elastic modulus between male and female. The mean, max and min values of the elastic modulus of compressive segment were significantly lower than those of normal spinal cord (p < 0.01). There was no significant correlation between age, BMI and normal segment spinal cord elasticity. There was a negative correlation between JOA scores and reduce ratio of elastic modulus (R2=0.18,p=0.03). The ICC of the normal segment elastic modulus was 0.959(95% CI: 0.912~0.982), and the ICC of the compressed segment elastic modulus was 0.832(95% CI: 0.660~0.921).

Conclusions: The spinal cord elastic modulus in patients with cervical spondylotic myelopathy measured by SWE is feasible. SWE could distinguish the normal and compressed spinal cord. The reduce ratio of elastic modulus could reflect the spinal cord dysfunction.